17) Sapir, A. Why are nematodes so successful extremophiles? Communicative & Integrative Biology, 14:1, 24-26.
16) Sapir, A. Not So Slim Anymore-Evidence for the Role of SUMO in the Regulation of Lipid Metabolism. Biomolecules 2020. 10(8), 1-20.
15) Shamsuzzama, Lebedev, R., Trabelcy, B., Goncalves, IL., Gerchman, Y., Sapir A. 2020. Metabolic Reconfiguration in C. elegans Suggests a Pathway for Widespread Sterol Auxotrophy in the Animal Kingdom. Current Biology 2020, 30, 3031-3038 e3037.
14) Goncalves, IL., Tal, S., Barki-Harrington, L., Sapir, A. 2020. Conserved statin-mediated activation of the p38-MAPK pathway protects Caenorhabditis elegans from the cholesterol-independent effects of statins. Molecular Metabolism 39, 101003.
13) Shih, P-Y., Lee, JS., Shinya, R., Kanzaki, N., Pires-daSilva, A., Badroos, JM., Goetz, E., Sapir, A*., Sternberg, PW*. 2019. Newly Identified Nematodes from Mono Lake Exhibit Extreme Arsenic Resistance. Current Biology 29:3339-3344.e426. *Corresponding authors.
12) Oks, O., Lewin, S., Goncalves, IL., Sapir A. 2018. The UPRmt protects Caenorhabditis elegans from mitochondrial dysfunction by upregulating specific enzymes of the mevalonate pathway. Genetics 209:457-473.
11) Sapir, A., Tsur, A., Koorman, T., Ching, K., Mishra, P., Bardenheier, A., Podolsky, L., Bening-Abu-Shach, U., Boxem, M., Chou, T.F., Broday, L., Sternberg, P.W. 2014. Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging. Proceedings of the National Academy of Sciences USA 111:E3880-3889.
10) Sapir, A., Dillman, A.R., Connon, S.A., Grupe, B.M., Ingels, J., Mundo-Ocampo, M., Levin, L.A., Baldwin, J.G., Orphan, V.J., Sternberg, P.W. 2014. Microsporidia-nematode associations in methane seeps reveal basal fungal parasitism in the deep sea. Frontiers in Microbiology 5:43.
9) Avinoam, O., Fridman, K., Valansi, C., Abutbul, I., Zeev-Ben-Mordehai, T., Maurer, U.E., Sapir, A., Danino, D., Grunewald, K., White, J.M., Podbilewicz, B. 2011. Conserved eukaryotic fusogens can fuse viral envelopes to cells. Science 332:589-592.
8) Sapir, A., Avinoam, O., Podbilewicz, B., Chernomordik, L.V. 2008. Viral and developmental cell fusion mechanisms: conservation and divergence. Developmental Cell 14:11-21.
7) Sapir, A., Choi, J., Leikina, E., Avinoam, O., Valansi, C., Chernomordik, L.V., Newman, A.P., Podbilewicz, B. 2007. AFF-1, a FOS-1-regulated fusogen, mediates fusion of the anchor cell in C. elegans. Developmental Cell 12:683-698.
6) Podbilewicz, B., Leikina, E., Sapir, A., Valansi, C., Suissa, M., Shemer, G., Chernomordik, L.V. 2006. The C. elegans developmental fusogen EFF-1 mediates homotypic fusion in heterologous cells and in vivo. Developmental Cell 11:471-481.
5) Sapir, A., Assa-Kunik, E., Tsruya, R., Schejter, E., Shilo, B.Z. 2005. Unidirectional Notch signaling depends on continuous cleavage of Delta. Development 132:23-132.
4) Folberg-Blum, A., Sapir, A., Shilo, B.Z., Oren, M. 2002. Overexpression of mouse Mdm2 induces developmental phenotypes in Drosophila. Oncogene 21:2413-2417.
3) Tsruya, R., Schlesinger, A., Reich, A., Gabay, L., Sapir, A., Shilo, B.Z. 2002. Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz. Genes and Development 16:222-234.
2) Reich, A., Sapir, A., Shilo, B. 1999. Sprouty is a general inhibitor of receptor tyrosine kinase signaling. Development 126:4139-4147.
1) Sapir, A., Schweitzer, R., Shilo, B.Z. 1998. Sequential activation of the EGF receptor pathway during Drosophila oogenesis establishes the dorsoventral axis. Development 125:191-200.
16) Sapir, A. Not So Slim Anymore-Evidence for the Role of SUMO in the Regulation of Lipid Metabolism. Biomolecules 2020. 10(8), 1-20.
15) Shamsuzzama, Lebedev, R., Trabelcy, B., Goncalves, IL., Gerchman, Y., Sapir A. 2020. Metabolic Reconfiguration in C. elegans Suggests a Pathway for Widespread Sterol Auxotrophy in the Animal Kingdom. Current Biology 2020, 30, 3031-3038 e3037.
14) Goncalves, IL., Tal, S., Barki-Harrington, L., Sapir, A. 2020. Conserved statin-mediated activation of the p38-MAPK pathway protects Caenorhabditis elegans from the cholesterol-independent effects of statins. Molecular Metabolism 39, 101003.
13) Shih, P-Y., Lee, JS., Shinya, R., Kanzaki, N., Pires-daSilva, A., Badroos, JM., Goetz, E., Sapir, A*., Sternberg, PW*. 2019. Newly Identified Nematodes from Mono Lake Exhibit Extreme Arsenic Resistance. Current Biology 29:3339-3344.e426. *Corresponding authors.
12) Oks, O., Lewin, S., Goncalves, IL., Sapir A. 2018. The UPRmt protects Caenorhabditis elegans from mitochondrial dysfunction by upregulating specific enzymes of the mevalonate pathway. Genetics 209:457-473.
11) Sapir, A., Tsur, A., Koorman, T., Ching, K., Mishra, P., Bardenheier, A., Podolsky, L., Bening-Abu-Shach, U., Boxem, M., Chou, T.F., Broday, L., Sternberg, P.W. 2014. Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging. Proceedings of the National Academy of Sciences USA 111:E3880-3889.
10) Sapir, A., Dillman, A.R., Connon, S.A., Grupe, B.M., Ingels, J., Mundo-Ocampo, M., Levin, L.A., Baldwin, J.G., Orphan, V.J., Sternberg, P.W. 2014. Microsporidia-nematode associations in methane seeps reveal basal fungal parasitism in the deep sea. Frontiers in Microbiology 5:43.
9) Avinoam, O., Fridman, K., Valansi, C., Abutbul, I., Zeev-Ben-Mordehai, T., Maurer, U.E., Sapir, A., Danino, D., Grunewald, K., White, J.M., Podbilewicz, B. 2011. Conserved eukaryotic fusogens can fuse viral envelopes to cells. Science 332:589-592.
8) Sapir, A., Avinoam, O., Podbilewicz, B., Chernomordik, L.V. 2008. Viral and developmental cell fusion mechanisms: conservation and divergence. Developmental Cell 14:11-21.
7) Sapir, A., Choi, J., Leikina, E., Avinoam, O., Valansi, C., Chernomordik, L.V., Newman, A.P., Podbilewicz, B. 2007. AFF-1, a FOS-1-regulated fusogen, mediates fusion of the anchor cell in C. elegans. Developmental Cell 12:683-698.
6) Podbilewicz, B., Leikina, E., Sapir, A., Valansi, C., Suissa, M., Shemer, G., Chernomordik, L.V. 2006. The C. elegans developmental fusogen EFF-1 mediates homotypic fusion in heterologous cells and in vivo. Developmental Cell 11:471-481.
5) Sapir, A., Assa-Kunik, E., Tsruya, R., Schejter, E., Shilo, B.Z. 2005. Unidirectional Notch signaling depends on continuous cleavage of Delta. Development 132:23-132.
4) Folberg-Blum, A., Sapir, A., Shilo, B.Z., Oren, M. 2002. Overexpression of mouse Mdm2 induces developmental phenotypes in Drosophila. Oncogene 21:2413-2417.
3) Tsruya, R., Schlesinger, A., Reich, A., Gabay, L., Sapir, A., Shilo, B.Z. 2002. Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz. Genes and Development 16:222-234.
2) Reich, A., Sapir, A., Shilo, B. 1999. Sprouty is a general inhibitor of receptor tyrosine kinase signaling. Development 126:4139-4147.
1) Sapir, A., Schweitzer, R., Shilo, B.Z. 1998. Sequential activation of the EGF receptor pathway during Drosophila oogenesis establishes the dorsoventral axis. Development 125:191-200.